Workshop Programme
Day 1 – Basics of NMR
NMR - Introduction & Basics:Covers basics of NMR spectroscopy mathematical treatment, energy levels, Larmor equation, resonance condition, brief introduction to instrumentation, extractable parameters from NMR spectrum - chemical shift and coupling constants, definition of chemical shift, shielding and deshielding, chemical shift scale, origin of coupling constants, Pascal's triangle, spin-spin splitting, splitting pattern, aliphatic and aromatic molecules as examples to decipher chemical shift and coupling constant, introduction to C13 NMR, interaction between H1-C13, decoupling, practical approach to NMR, sample handling, integration, quantitative NMR, introduction to 2D NMR, Homonuclear and Heteronuclear 2D NMR experiments for structural elucidation, summary
Structure by NMR: Information from 1D and 2D NMR experiments, overview of NMR experiments used for structural elucidation, Observables from homo-nuclear and hetero-nuclear 2D NMR experiments, identification of spin systems, establishing connectivity, mapping homo-nuclear and hetero-nuclear coupling constants, exploiting long-range hetero-nuclear coupling constants, determining fragments and connecting fragments, deriving the skeleton of the molecule, elucidating the structure of a saccharide molecule.
Show & Tell NMR: A walk through on 500 MHz NMR spectrometer, detailed explanation of superconducting magnet, hardware, probe, and software, sample preparation guidelines and checkpoints, workflow of analysis, data processing.
Day 2 – Advance NMR Techniques – 2D, QNMR (Quantification), FFC Relaxometry
Structure by 2D NMR Information from 1D and 2D NMR experiments, overview of NMR experiments used for structural elucidation, Observables from homo-nuclear and hetero-nuclear 2D NMR experiments, identification of spin systems, establishing connectivity, mapping homo-nuclear and hetero-nuclear coupling constants, exploiting long-range hetero-nuclear coupling constants, determining fragments and connecting fragments, deriving the skeleton of the molecule, elucidating the structure of a saccharide molecule.
qNMR(Quantification by NMR): Introduction to qNMR, usage of qNMR, concentration and purity determination, calibration standard, practical aspects, importance of experimental conditions, integration and peak analysis, calculations to determine concentration and purity, a couple of practical examples.
FFC Relaxometer: The power of Fast Field Cycling NMR relaxometry as an analytical technique Introduction to Fast Field Cycling (FFC) as a low-field NMR technique [1] which allows the measurement of the T1 (or R1=1/T1) of a sample over a wide range of magnetic field strengths (from 10kHz to 40MHz) using just one instrument. How FFC finds application in many different sectors such as: MRI contrast agents, liquids in confined spaces (e.g. oil-bearing rocks and catalysts), electrolytes, proteins, batteries, foodstuff and plastic/polymers industry.
Day 1 (Monday)
Introduction to Basic NMR & Demo
Date | Sessions | Topics | Time |
---|---|---|---|
17th October 2022 |
Inauguration & Opening Speech | 01.30 pm to 02.00 pm | |
Session 1 | Introduction & Basics of NMR | 02.00 pm to 03.30 pm | |
Tea / Coffee Break | 03.30 pm to 03.45 pm | ||
Session 2 | Structure Determination by NMR | 03.45 pm to 05.15 pm | |
Session 3 | Interaction, Q&A | 05.15 pm to 05.30 pm |
Day 2 (Tuesday)
Advance NMR Techniques & FFC Relaxometry(For Industry)
Date | Sessions | Topics | Time |
---|---|---|---|
18th October 2022 |
Session 4 | Structure By 2D NMR | 09.30 am to 11.00 am |
Tea / Coffee Break | 11.00 am to 11.30 am | ||
Session 5 | Advance NMR Techniques (2D/QNMR) | 11.30 am to 01.00 pm | |
Lunch Break | 01.00 pm to 02.00 pm | ||
Session 6 | FFC NMR Relaxometry Introduction | 02.00 pm to 03.00 pm | |
Tea / Coffee Break | 03.00 pm to 3.30 pm | ||
Session 7 | FFC relaxometry Applications | 03.30 pm to 04.30 pm | |
session 8 | Interaction, Q&A | 04.30 pm to 05.00 pm |